Nitrogen mustard compounds
Medchemexpress LLC Camonsertib | 2417489-10-0 | 99.99% | 410.47 | 100 MG
Camonsertib (RP-3500) is an orally active, selective ATR kinase inhibitor (ATRi) with an IC50 of 1.00 nM in biochemical assays. It demonstrates 30-fold selectivity for ATR over mTOR (IC50=120 nM) and >2,000-fold selectivity over ATM, DNA-PK, and PI3Kα kinases. Camonsertib exhibits potent antitumor activity.
- Orally active, selective ATR kinase inhibitor
- IC50 of 1.00 nM for ATR in biochemical assays
- Exhibits 30-fold selectivity for ATR over mTOR
- Shows >2,000-fold selectivity over ATM, DNA-PK, and PI3Kα kinases
- Demonstrates potent antitumor activity
Medchemexpress LLC (E)-5-(2-(quinolin-4-yl)vinyl)benzene-1,3-diol | 1016897-10-1 | 98.1% | 263.29 g/mol | C17H13NO2 | 100MG
RV01 is a small-molecule resveratrol analogue that inhibits acetaldehyde dehydrogenase (ALDH) and has been reported to reduce DNA damage; it is intended for biochemical and pharmacology research applications. The compound is supplied as a light-yellow powder (also available as DMSO solutions), has a molecular weight of 263.29 g/mol, and a typical purity of 98.1%; follow recommended storage conditions for stability.
eMolecules 2377151-10-3 | Medchem Express | ZL0580 | 5mg | 527574223 | HY-126428 | 532.54 | C25H23F3N4O4S
Medchem Express | Cefuroxime (sodium) | 500mg | 491484622 | HY-B1256 | 56238-63-2 | MFCD09878727 | 446.370 | C16H15N4NaO8S
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Medchemexpress LLC ML-184 25mg | 794572-10-4 | 470.63 g·mol⁻¹ | C25H34N4O3S | 25 MG
ML-184 is a small-molecule research compound described as a GPR55 agonist and used in cell-based and pharmacological studies. It is supplied as a high-purity solid for laboratory research and is identified by CAS 794572-10-4.
- Acts as a GPR55 agonist for pharmacology and cell studies.
- High reported purity suitable for research applications.
- Molecular formula C25H34N4O3S and molecular weight 470.63 g·mol⁻¹.
- Supplied as a solid in a 25 mg package for benchtop use.
- CAS number 794572-10-4 provides an unambiguous chemical identifier.
Medchemexpress LLC Mizagliflozin (DSP-3235 free base) | 666843-10-3 | 99.2% | 564.67 g/mol | C28H44N4O8 | 10 MG
Mizagliflozin is a potent, orally active, selective SGLT1 inhibitor used in research on postprandial glucose regulation and constipation amelioration. It exhibits a Ki of approximately 27 nM for human SGLT1 and about 303-fold selectivity versus SGLT2.
- Selective SGLT1 inhibition (Ki ≈ 27 nM).
- High purity (99.2%).
- Molecular formula C28H44N4O8; molecular weight 564.67 g/mol.
- Solid, off-white to light yellow appearance.
- Store at 4°C protected from light; in solution store -80°C for long-term.
Aobchem N-(2-Chloroethyl)-2-methylbenzamide | 95% | CAS 161194-80-5 | C10H12ClNO | 5g
N-(2-Chloroethyl)-2-methylbenzamide | 95% | CAS 161194-80-5 | C10H12ClNO | 5g
Medchemexpress LLC ZL0580 | 2377151-10-3 | 99.4% | 532.53 | 50 MG
ZL0580 is a structurally similar analog of ZL0590. It induces epigenetic suppression of HIV by selectively binding to the BD1 domain of BRD4. This compound suppresses HIV by inhibiting Tat transactivation and transcription elongation, and by inducing repressive chromatin structure at the HIV promoter. It is intended for research use only.
- Induces epigenetic suppression of HIV
- Selectively binds to BD1 domain of BRD4
- Inhibits Tat transactivation and transcription elongation
- Induces repressive chromatin structure at the HIV promoter
- Demonstrates low toxicity at effective concentrations (e.g., 8 μM in PBMCs)
- Suppresses both PMA-stimulated and basal HIV transcription
- Shows almost complete loss of productive HIV infection in CD4+ T cells at 8 μM
![Medchemexpress LLC Ethyl 3-[(3-methoxynaphthalen-1-yl)amino]benzoate | 2374831-10-2 | 98.1% | 321.37 | C20H19NO3 | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000235955.png-250.jpg)
Medchemexpress LLC Ethyl 3-[(3-methoxynaphthalen-1-yl)amino]benzoate | 2374831-10-2 | 98.1% | 321.37 | C20H19NO3 | 100MG
CDC25B-IN-1 is a small-molecule inhibitor of the CDC25B phosphatase used for biochemical and cellular research. Reported as compound 4a, it inhibits CDC25B with a Ki of 8.5 μM, reduces cell proliferation and colony formation, and induces G2/M cell-cycle arrest. The material is typically supplied as a light brown oil or as a DMSO solution for assay use.
- Inhibits CDC25B with a reported Ki of 8.5 μM.
- Reduces cell proliferation and colony formation in cellular assays.
- Induces G2/M cell-cycle arrest.
- Molecular formula C20H19NO3; molecular weight 321.37.
- High purity (approximately 98.1%; may vary by batch).
- Available in multiple quantities and solution formats for assay convenience.
- Storage recommendations include refrigeration under inert atmosphere and low-temperature storage in solvent.
eMolecules 3302-10-1 | 3,5,5-Trimethylhexanoicacid | Ambeed | MFCD00020507 | 158.241 | C9H18O2 | 98.000 | CC(CC(O)=O)CC(C)(C)C | 100g | 624121817
3,5,5-Trimethylhexanoicacid | Ambeed | 3302-10-1 | MFCD00020507 | 158.241 | C9H18O2 | 98.000 | CC(CC(O)=O)CC(C)(C)C | 100g | 624121817
Medchemexpress LLC 2-chloroethyl (2-chloroethyl)phosphonate | 17378-30-2 | MFCD24393365 | 206.99 | C4H9Cl2O3P | 50 MG
2-Chloroethyl (2-chloroethyl)phosphonate is an organophosphorus compound used as an intermediate in organic synthesis and building phosphonate-containing molecules for research applications. It is provided as an analytical-grade reagent; consult the certificate of analysis for storage and characterization details.
- Organophosphorus synthesis intermediate.
- Molecular formula C4H9Cl2O3P.
- Molecular weight 206.99 g/mol.
- CAS number 17378-30-2.
- Packaged as a 50 MG unit.
- Refer to the certificate of analysis for purity and storage instructions.
Medchemexpress LLC Senkyunolide A | 63038-10-8 | 192.26 | 5 MG
Senkyunolide A is a phthalide with anticancer activity, acting as an anti-tumor cell proliferation agent. It offers neuroprotective effects by decreasing protein phosphatase PP2A and α-synuclein phosphorylation, and inhibits osteoarthritis by modulating the NLRP3 signaling pathway. Furthermore, it suppresses the expression of CD137, a biomarker for atherosclerosis.
- Inhibits proliferation of HT-29 and CCD-18Co cells.
- Decreases high expression of CD137 in TNF-α treated MAECs cells.
- Enhances cell viability and reduces apoptosis in PC12 cells.
- Stimulates cell proliferation and curbs apoptosis in IL-1β-treated chondrocytes.
- Inhibits cell inflammation by blocking the NLRP3 signaling pathway.
- Demonstrates improvement in mouse models of osteoarthritis, alleviating articular cartilage destruction.
Medchemexpress LLC KB-5492 (anhydrous) | 129200-10-8 | 99.5% | 546.57 | 5 MG
KB-5492 anhydrous is a potent and selective inhibitor of the sigma receptor, inhibiting specific [3H]1,3-di(2-tolyl)guanidine (DTG) binding with an IC50 of 3.15 μM. It also functions as an anti-ulcer agent, preventing ethanol- and acidified aspirin-induced increases in 51Cr release from gastric epithelial cells in vitro, and macroscopic lesions in the gastric mucosa in vivo.
- Potent and selective sigma receptor inhibitor
- Inhibits specific DTG binding in a concentration-dependent manner
- Prevents ethanol- and acidified aspirin-induced increases in 51Cr release from gastric epithelial cells
- Prevents macroscopic lesions in the gastric mucosa in animal models
- Suitable for research use only
eMolecules 213211-10-0 | Medchem Express | BIRT 377 | 5mg | 758391260 | HY-110117 | MFCD28166481 | 442.13 | C18H15BrCl2N2O2
Medchem Express | Isoorientin | 1mg | 446275345 | HY-N0767 | 4261-42-1 | MFCD00017433 | 448.380 | C21H20O11
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Medchemexpress LLC Flesinoxan | 98206-10-1 | 99.9% | 10 MG
Flesinoxan is a potent, selective 5-hydroxytryptamine 1A (5-HT1A) receptor agonist used for pharmacological research. Supplied as a high-purity solid, it is suitable for in vitro and in vivo studies when handled and stored per recommended conditions.
- Potent, high-affinity 5-HT1A receptor agonist.
- High purity suitable for research applications.
- Soluble in DMSO; in vivo formulations documented.
- Stable under recommended storage conditions.
- Available in small research-scale pack sizes.